Senior Bioinformatics Role at Cancer Diagnostics Company

Job Summary

Genomic Expression is seeking a senior-level bioinformatician to run our bioinformatics operations and lead further development of our OneRNA platform. This person must be skilled in all facets of bioinformatics analysis, and possess deep expertise in analysis of tumor RNA and DNA sequencing data.  You will be working alongside pioneers in oncology, bench scientists, engineers, and software developers to develop new cancer diagnostic tests and better match cancer patients to treatment options.  

Responsibilities and Duties

• Develop novel methods to analyze and interpret tumor sequencing data in a clinical context
• Create and optimize new bioinformatics pipelines 
• Perform analysis of experimental data sets and present results to the lab team
• Work with external collaborators to design and interpret cancer research studies
• Supervise routine operation of our sequencing bioinformatic analysis pipeline
• Monitor sequencing data quality and work with lab team to address deviations
• Represent bioinformatics needs in company planning related to IT infrastructure
• Create weekly, quarterly and longer term plans related to genomic data analysis and infrastructure
• Supervise writing of data-related protocols and SOPs
• Hire and manage and mentor junior bioinformatics staff
• Hire and manage external contractors working  for data-related projects

Qualifications, Skills and Expertise: 

• PhD in Bioinformatics, Computational Biology or Biological Sciences with strong quantitative background involving the analysis of next generation sequencing data (including RNA sequencing data),  or Master’s degree with equivalent research experience
• Experience working in both academia and industry
• Demonstrated ability to innovate and solve challenging problems
• Deep knowledge of genomics, bioinformatics, biostatistics and cancer biology
• Experience in development, selection, validation an operation of tools and open source software related to data analysis such as gene expression, pathway identification, variant calling, copy number variation identification, structural variants identification, gene fusion, allele specific gene expression, novel transcripts, etc.
• Experience in interpreting data derived from NGS sequencing in the context of cancer research
• Ability to lead interdisciplinary teams to plan experiments and interpret resulting data
• Demonstrated ability to supervise and mentor less experienced data scientists, including entry level staff and students 
• Excellent written and verbal communication skills
• Experience developing scripts for processing NGS data in languages that include Python and R 
• Experience with cloud computing platforms such as AWS
• Understanding or willingness to understand regulatory environments such as HIPAA and CLIA
• MUST BE PREPARED TO ADOPT AN ENGINEERING MINDSET: BUILD, TEST, DEPLOY, REPEAT

Company Overview

At Genomic Expression, we are building a company to address the urgent need for better cancer treatments. Currently only 1 out of 4 cancer treatment prolongs life, yet we spend $100 billion on drugs and 8 million patients die every year from the disease.  Genomic Expression is changing this paradigm by sequencing tumor RNA to find the best drug for the patient, and the best patient for the drug. With four funded programs in various cancer types, including breast and ovarian cancer, Genomic Expression is a first mover in making RNA sequencing actionable in oncology.

• 1 min Product Video: http://bit.ly/OneRNAMovie
• 1 min Company video: http://bit.ly/GExCorp
• Website: http://www.genomicexpression.com/
• Twitter: @dnabarcode (+ 50,000 followers)

Company DNA:
Our company culture is based on respect for the individual and admiration for creativity and intellect. We will honor anybody’s ability to create value for our company. We are team oriented and expect our employees to take responsibility and initiative. 

Location:

We are prioritizing candidates from the greater Boston area.  This position will be located at Genomic Expression's headquarters in Beverly, Massachusetts about 40 minutes north of Boston.  

Benefits:

You will work with an entrepreneurial team that offers significant growth opportunities and the opportunity to improve the care of cancer patients. Company benefits include paid vacation and employee stock options.